I kēia manawa, aia ma kahi o 81 mau ʻano lāʻau anti-tumor i hoʻohana mau ʻia i nā lāʻau lapaʻau.1. Hoʻokaʻawale ʻia nā lāʻau anti-tumor e like me ko lākou kumu a me ka hana o ka hana.Hoʻokaʻawale ʻia i nā lāʻau alkylating, antimetabolites, antibiotics, mea kanu, hormones a me nā lāʻau ʻē aʻe.ʻO nā lāʻau lapaʻau ʻē aʻe e pili ana i ka platinum, asparaginase, nā lāʻau lapaʻau i hoʻopaʻa ʻia, a me nā mea ʻē aʻe, me ka waiho ʻole ʻana i nā reagents biological a me ka gene therapy.ʻAʻole hiki i kēia hoʻohālikelike ke hōʻuluʻulu i ka ulu ʻana o nā lāʻau anti-tumor i kēia manawa.ʻO ka lua, ʻo ka hoʻohālikelike ʻē aʻe e pili ana i nā molecular targets o nā lāʻau lapaʻau, i māhele ʻia i nā ʻāpana he nui.ʻO ka ʻāpana mua nā lāʻau lapaʻau e hana ana i ke ʻano kemika o DNA, e like me ka alkylating a i ʻole nā ​​pūhui platinum.ʻO ka lua o nā lāʻau lapaʻau e pili ana i ka synthesis nucleic acid, e like me nā antimetabolites.ʻO ke kolu o ka ʻāpana ʻo ia ka lāʻau lapaʻau e hana ana i ka template DNA, pili i ka transcription a me ka inhibition o DNA, a ke kāohi i ka synthesis RNA ma ka hilinaʻi ʻana i ka RNA polymerase.ʻO ka hā o nā lāʻau lapaʻau e pili ana i ka synthesis protein, e like me paclitaxel, vinblastine a pēlā aku.ʻO ka ʻāpana hope loa nā ʻano lāʻau lapaʻau ʻē aʻe, e like me nā hormones, aspartic acid, targeted therapy drugs, a me nā mea ʻē aʻe, akā ke ulu wikiwiki nei nā lāʻau anti-tumor o kēia manawa, a ʻaʻole hiki i nā ʻāpana i luna ke hōʻuluʻulu i nā lāʻau i loaʻa a me nā lāʻau lapaʻau e pili ana. e komo i ka halemai..“

I kēia manawa, nui nā lāʻau anti-tumor i ka hana lapaʻau.ʻo kahi laʻana,oxaliplatin, fluorouracil, a hiki ke hoʻohana ʻia ka irinote no nā ʻōpū o ka ʻōpū.Hiki ke mālama ʻia nā maʻi me ka maʻi maʻi ʻōpū me nā lāʻau lapaʻau e like mecisplatinapaclitaxel.Ma keʻano laulā, koho nā maʻi kanesa ʻokoʻa i nā lāʻau lapaʻau like ʻole.Eia kekahi, hiki ke mālama ʻia nā maʻi maʻi maʻi me nā lāʻau molecular targeted, e like me erlotinib, osimertinib, cetuximab a me nā lāʻau lapaʻau ʻē aʻe.

ʻO nā lāʻau anti-tumor maʻamau e hoʻopiʻi i ka CIPNPaclitaxel, Platinum, Vinblastine,Methotrexate, Fluorouracil, Ifosfamide,Cytarabine, Fludarabine, Thalidomide,ʻO Bortimiazolea laila.

Hoʻohana ʻo Paclitaxel i ka mea ulu aʻalolo e hōʻemi a hoʻohuli paha i ka neurotoxicity;hoʻohana ʻo cisplatin i ka glutathione liʻiliʻi a me ka amifostine e pale i ka neuropathy i hoʻokumu ʻia e ia;ʻAʻole pili ka oxaliplatin i ka hoʻoulu ʻana i ke anuanu i ka wā e hoʻohana ai e pale i ka hoʻoulu ʻana i ke anuanu mai ka hoʻopili ʻana i nā aʻalolo peripheral.Hiki i ka ifosfamide ke koho i ka methylene blue e pale ai i ka neurotoxicity;hoʻohana i ka thiamine no ka fluorouracil hiki ke pale i nā aʻalolo Ka hopena ʻona.