USP 175865-59-5 Valganciclovir hydrochloride no ka Antiviral
| Huahanainoa | ʻO Valganciclovir hydrochloride |
| Nā huaʻōlelo like | L-Valine,2-[(2-aMino-1,6-dihydro-6-oxo-9H-purin-9-yl)Methoxy]-3-hydroxypropylester,hydrochloride(1:1);2-[(2- amino-6-oxo-6,9-dihydro-3H-purin-9-yl)methoxy]-3-hydroxypropyl(2S)-2-amino-3-methylbutanoatehydChemicalbookrochloridehydrate;L-Valine,2-[(2-amino- 1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropylester,monohydrochloridehydrate |
| CAS No. | 175865-59-5 |
| Ka nana aku | Keʻokeʻo keʻokeʻo keʻokeʻo keʻokeʻo |
| ʻĀpana Molekala | C14H22N6O5.HCl |
| Kaumaha Molekala | 390.83 |
| Hoʻohana | Lapaʻau Lapaʻau a i ʻole ke kumu noiʻi |
| Hoʻopili | E like me kāu noi |
| Waihona | E mālama i loko o nā pahu paʻa a me ka māmā ma kahi anuanu |
| ʻO ka Valganciclovir hydrochloride:175865-59-5 | ||
| Nā mea | Kūlana | Nā hualoaʻa |
| Ka nana aku | Keʻokeʻo keʻokeʻo keʻokeʻo keʻokeʻo | pauda keʻokeʻo |
| ʻIkepili | Infrared Absorption: E pili ana i ka maʻamau kuhikuhiUltraviolet Absorption: E pili ana i ka maʻamau kuhikuhiʻO kahi hopena i loko o ka wai (1 i ka 20) e hoʻokō i nā koi o nā hoʻokolohua no Chloride | Hoʻokō Hoʻokō
Hoʻokō |
| ʻO ka waiʻona isopropyl | ≤1.0% | 0.13% |
| Wai | ≤8.0% | 4.5% |
| Nā metala kaumaha | ≤20ppm | Hoʻokō |
| Pd | ≤10ppm | ＜10ppm |
| Koena ma luna o ke ahi | ≤0.1% | 0.02% |
| ʻO nā haumia pili | Valganciclovir: /Ganciclovir: ≤1.5%Guanine: ≤1.5% Methoxymethylguanine: ≤0.3% Isovalganciclovir: ≤0.5% Monoacetoxyganciclovir: ≤0.15% Hikina Bis-valine o ganciclovir: ≤0.1% Homologue o valganciclovir: ≤0.25% Imp H: ≤0.1% Imp I: ≤0.1% Ganciclovir monopropionate: ≤0.15% Valganciclovir dimer (stereoisomer A): ≤0.1% Valganciclovir dimer (stereoisomer B): ≤0.1% Valganciclovir dimer (stereoisomer C): ≤0.1% Hoʻokahi mea haumia ʻē aʻe i ʻike ʻia: ≤0.1% Huina haumia ʻē aʻe i ʻike ʻia: ≤0.1% Ganciclovir mono-N-methyl valinate (Ho'āʻo 2):≤0.3% Hoʻokahi haumia ʻike ʻole ʻia (Test 1 a me 2): ≤0.1 % Huina haumia ʻike ʻole ʻia (Test 1 a me 2): ≤0.25% Huina haumia (Ho'āʻo 1 a ho'āʻo 2): ≤3.0 | /0.02%0.01% 0.03% 0.02% ND 0.04% 0.01% 0.01% 0.004% ND ND ND ND 0.04% ka nui 0.04%
0.02% 0.02% ka nui 0.13% 0.78% |
| Diastereomer lākiō | 45:55 a 55:45 | 54:46 |
| Enantiomeric maemae o valganciclovir | ≥97.0% | 99.9% |
| ʻO ka hōʻike HPLC | 97.0%～102.0% | 98.8% |
| Ka hopena: pili me USP40. | ||
ʻIkepili Hui
√ Ka ʻike piha o ka papa hoʻokele ma ka hale hana a me nā mea ʻenehana akamai; √ ʻO ka maikaʻi ka mea i manaʻo nui ʻia, ʻōnaehana QC koʻikoʻi; √ 11 makahiki i ʻike i ka lawe ʻana i nā hui kūʻai; √ Keʻena hana R&D kūʻokoʻa; √ ʻElua mau papa hana GMP lōʻihi i pūlima ʻia; √ Nā waiwai waiwai o nā hale hana palaualelo no ka papahana maʻamau; √ Kiʻekiʻe Efficiency hui hana me ke ala mau.
